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BIO 311: Cell Biology

Course Description

Cell Biology is the advanced study of cells and the major biomolecules that comprise them. This course will focus on both the structural and physiological aspects of normal and abnormal cell functioning and investigate key specialized molecular functions that cells perform such as metabolism, growth, communication, replication, dysfunction, and death. Current research methods and technology will also be investigated.

Prerequisites

  • BIO 110: Biology 1 with Lab
  • CHE 101: Chemistry with Lab
  • ENG 101: English Compostion 1
  • ENG 102: English Composition 2

Student Learning Outcomes (SLOs)

Upon successful completion of the course, the student will be able to:

  1. Establish a clear understanding of the structural and functional complexity of the eukaryotic cell.
  2. Summarize the various internal mechanisms of cellular control, regulation and motility.
  3. Discuss the various types of cell transport pathways across a cellular membrane.
  4. Explain the various signaling pathways and modes of communication between cells.
  5. Illustrate an In-depth understanding of cellular organelles and their physiological functions.
  6. Differentiate the roles of the major biological molecules as well as the process of ATP formation.
  7. Outline the steps of DNA replication and repair and gene expression.
  8. Explain cellular reproduction, the cell cycle and apoptosis.
  9. Evaluate the genetics and pathophysiology of Cancer.
  10. Identify the cellular complexity of the immune response.
  11. Investigate current research methods and laboratory technology in modern day cellular biology.
  12. Development proficiency in reading, writing and evaluating scientific literature.

General Education Outcomes (GEOs)

Please check the applicable GEOs for this course, if any, by outcomes at GEO Category Search, or by subject area at GEO Discipline Search.

Course Activities and Grading

Assignment(s)

Weight

Discussions (Weeks 1-15)

15%

Case Studies (Weeks 1-14)

15%

Exams (Weeks 3, 7, 11 & 14)

25%

Journal Article Critique (Weeks 6 & 12)

20%

Final Exam (Week 15)

25%

Total

100%

Required Textbooks

Available through our online bookstore

  • Karp, Gerald. (2016). Cell and Molecular Biology: Concepts and Experiments. 8th ed. John Wiley & Sons Publishing. ISBN-13: 978-1-118-88614-4 [Looseleaf Version]

Course Schedule

Week

SLOs

Readings and Exercises

Assignment(s)

1

1-7

Topics: Basic Properties and Classes of Cells & Chemical Basis of Life

 Readings:

  • Chapter 1
  • Chapter 2
  • Read assigned chapters
  • Review the lecture material and powerpoint
  • Participate in the Discussions
  • Submit Case Study 1

2

1,3,4,5,6

Topics: Bioenergetics, Enzymes and Metabolism

 Reading:

  • Chapter 3
  • Read assigned chapter
  • Review the lecture material and powerpoint
  • Participate in the Discussions
  • Submit Case Study 2

3

1-6

Topics: Structure and Function of The Plasma Membrane

 Reading:

  • Chapter 4
  • Read assigned chapter
  • Review the lecture material and powerpoint
  • Participate in the Discussions
  • Submit Case Study 3
  • Complete Exam 1

Exam #1
Chapters 1-4
SLOs 1-7

4

1-6

Topics: Aerobic Respiration and the Mitochondrion

 Reading:

  • Chapter 5
  • Read assigned chapter
  • Review the lecture material and powerpoint
  • Participate in the Discussions
  • Submit Case Study 4

5

1-5

Topic: Photosynthesis and the Chloroplast

 Reading:

  • Chapter 6
  • Read assigned chapter
  • Review the lecture material and powerpoint
  • Participate in the Discussions
  • Submit Case Study 5

6

1-4

Topic: Interactions Between Cells and Their Environment

 Reading:

  • Chapter 7
  • Read assigned chapter
  • Review the lecture material and powerpoint
  • Participate in the Discussions
  • Submit Case Study 6
  • Submit Journal Article Review 1

7

1,2,3,5

Topics: Cytoplasmic Membrane Structure: Structure, Function, and Membrane Trafficking

Reading:

  • Chapter 8
  • Read assigned chapter
  • Review the lecture material and powerpoint
  • Participate in the Discussions
  • Submit Case Study 7
  • Complete Exam 2

Exam #2
Chapters  5-8
SLOs 1-6

8

1,2,3,5

Topics: The Cytoskeleton and Cell Motility

 Reading:

  • Chapter 9
  • Read assigned chapter
  • Review the lecture material and powerpoint
  • Participate in the Discussions
  • Submit Case Study 8
  • Submit Journal Article Review 2

9

1,2,7

Topics: Structure and Function of The Plasma Membrane

Reading:

  • Chapter 10
  • Chapter 11
  • Read assigned chapters
  • Review the lecture material and powerpoint
  • Participate in the Discussions
  • Submit Case Study 9

10

1,2,7

Topic: Control of Gene Expression

Reading:

  • Chapter 12
  • Read assigned chapter
  • Review the lecture material and powerpoint
  • Participate in the Discussions
  • Submit Case Study 10

11

1,2,7

Topics: DNA Replication and Repair

Reading:

  • Chapter 13
  • Read assigned chapter
  • Review the lecture material and powerpoint
  • Participate in the Discussions
  • Submit Case Study 11
  • Complete Exam 3

Exam #3
Chapters 9-13
SLOs 1,2,3,5,7

12

1,2,3,4,7

Topic: Cellular Reproduction

Reading:

  • Chapter 14
  • Read assigned chapter
  • Review the lecture material and powerpoint
  • Participate in the Discussions
  • Submit Case Study 12
  • Submit Journal Article Review 2

13

1,2,4

Topic: Cell Signaling and Signal Transduction

Reading:

  • Chapter 15
  • Read assigned chapter
  • Review the lecture material and powerpoint
  • Participate in the Discussions
  • Submit Case Study 13

14

1,2,4,6

Topics: DNA Replication and Repair

Reading:

  • Chapter 17
  • Read assigned chapter
  • Review the lecture material and powerpoint
  • Participate in the Discussions
  • Submit Case Study 14
  • Complete Exam 4

Exam #4
Chapters 14,15 &17
SLOs 1,2,3,6,7

15

1,2,3,4

Topics: Cancer Cell, Techniques in Cell and Molecular Biology

Reading:

  • Chapter 16
  • Chapter 18
  • Read assigned chapter
  • Review the lecture material and powerpoint
  • Participate in the Discussions
  • Complete Final Exam

Final Exam
Chapters 1-18
SLOs 1-7

COSC Accessibility Statement

Charter Oak State College encourages students with disabilities, including non-visible disabilities such as chronic diseases, learning disabilities, head injury, attention deficit/hyperactive disorder, or psychiatric disabilities, to discuss appropriate accommodations with the Office of Accessibility Services at OAS@charteroak.edu.

COSC Policies, Course Policies, Academic Support Services and Resources

Students are responsible for knowing all Charter Oak State College (COSC) institutional policies, course-specific policies, procedures, and available academic support services and resources. Please see COSC Policies for COSC institutional policies, and see also specific policies related to this course. See COSC Resources for information regarding available academic support services and resources.